Fixed-parameter algorithms for protein similarity search under mRNA structure constraints
نویسندگان
چکیده
منابع مشابه
Fixed-Parameter Algorithms for Protein Similarity Search Under mRNA Structure Constraints
In the context of protein engineering, we consider the problem of computing an mRNA sequence of maximal codon-wise similarity to a given mRNA (and consequently, to a given protein) that additionally satisfies some secondary structure constraints, the so-called MRSO problem introduced in [2]. Since the MRSO problem is known to be APX-hard [7], Bongartz proposed in [7] to attack the problem using...
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ژورنال
عنوان ژورنال: Journal of Discrete Algorithms
سال: 2008
ISSN: 1570-8667
DOI: 10.1016/j.jda.2008.03.004